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“The pictures show lips that likely had newly placed filler,” says dermatologist Dr. Lauren Moy. “It takes a little time for swelling/bruising and filler to settle.”

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Dr. Moy tells Byrdie that NAD+ infusions have minimal clinical trial data in humans, and they have a rapid breakdown rate that limits bioavailability. Interestingly, though, precursor oral supplements have been around for a while, and they’re both well-tolerated and more thoroughly studied in middle-aged and older adults. She does point out that in rodent trials, an IV form of an NAD+ precursor delivered immediately after cardiac arrest improved survival rates and future cardiac function.

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